Fine particulate matter potentiates Th17-cell pathogenicity in experimental autoimmune uveitis via ferroptosis

The effect of fine particulate matter (PM2.5) on the development of uveitis remains unclear.Therefore, this study was designed to investigate the role of PM2.5 in experimental autoimmune uveitis (EAU) and its potential mechanism.Our results showed that PM2.5 could exacerbate the activity of EAU, as evidenced by severer clinical and pathological cha

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Design and Implementation of Adaptable Self-Protection Plans for Public Buildings: A Nursing Home Case in Spain

COVID-19 is reflecting the importance of self-protection plans in nursing homes, especially when it concerns persons of older age.Self-protection plans intend to prevent and control the risks of residential buildings.The goal of this research is to develop a design process for self-protection plans of public buildings, and specifically a nursing ho

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Disease history and medication use as risk factors for the clinical manifestation of type 1 diabetes in children and young adults: an explorative case control study.

BACKGROUND: There is a highly variable asymptomatic period of beta cell destruction prior to the clinical presentation of type1 diabetes.It is not well known what triggers type 1 diabetes to become a clinically overt disease.This explorative study aimed to identify the association between disease history/medication use and the clinical manifestatio

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